July 2009 - Donation to the Center for Molecular Therapeutics
In July 2009, TargetCancer made its first donation to the Center for Molecular Therapeutics at the Massachusetts General Hospital Cancer Center. Paul himself chose the Center for its cutting-edge therapies that treat the patient, not just the disease.
The lab’s Scientific Director, Dr. Jeffrey Settleman, wrote us in response to the donation.
His letter read, in part:
“I oversee a group of 20 extremely dedicated scientists who work tirelessly toward making new discoveries that will ultimately improve treatment strategies for cancer patients. One of the major areas of focus of our research involves the concept of "personalized cancer medicine".
In short, this means matching each patient with the right drugs. The fact is that there are many very good cancer drugs available, but they only seem to work well in a small fraction of treated patients. And we are starting to understand why that is.
We are beginning to appreciate the enormous complexity of cancer, and the fact that it is really hundreds of different diseases that fall under a single classification. In some sense, every patient's case is unique, and is defined by a unique genetic fingerprint. As we begin to closely examine the genetic fingerprints present within individual cancers, we are also beginning to be able to develop treatment strategies, based on that information, that are tailored to individual patients…
Paul's generous gift is already being put to great use in our research program, and will undoubtedly help us to make those next vital discoveries that will lead to improved clinical outcomes for many of our patients.
Although I only met Paul once, he certainly made a lasting impression with his genuine warmth and positive outlook. Hearing of his passing sadly reminds me that we still have important work to do- but I am certain that we are on the right track."